In the Media

 June 2005
Cost of Transplant Surgery Only Part of the Problem
What if the only thing standing in your way of a kidney transplant was not the cost of the surgery, but the cost of the medications to keep you alive afterward? (WTOC TV)
Long-Term Outcomes of Children with End-Stage Renal Disease
Editorial commentary from Pediatric Nephrology. Among the long list of potential problems these children face includes a risk of getting cancer that is ten times higher than the general population; skin cancer and non-Hodgkin lymphomas are most commonly reported. 
Amgen Contributes $3.9 Million to California Drug Ballot Effort
California voters will choose between two competing prescription-drug discount initiatives in the Nov. 8 special election. (Sacromento Bee via Ventura County Star - registration required)
Study Finds Hemodialysis Patients Have 9 Physical and Emotional Symptoms on Average
Abstract from JASN Express.
Japanese Scientists Cure Acute Renal Failure in Rats With Adult Stem Cells
Article from LifeNews.com. Also see the abstract in the Journal of Cell Biology. 
Stem Cell Transplant Succeeds in Curing Kidney Failure in Rats
A research team led by the University of Tokyo has succeeded in curing renal failure in rats by transplanting somatic stem cells of kidneys from healthy rats. Mainichi Daily News.
Breakthrough Isolating Embryo-quality Stem Cells From Blood
New York Times Examines Effort by Steve Case To Reform Health Care System
News summary from Kaiser Network.
Breakthrough Study Finds Adult Stem Cells Show Same Ability to Self-Renew as Embryonic
Press release from Children's Hospital of Pittsburgh
Improved Diabetes Management Could Save $72 Billion in Next Decade
Whose Kidney Is It, Anyway?
Commentary from RealClear Politics.
Should Society "Appropriate" Needed Kidneys for Transplantation?
Abstract of personal opinion piece from Nephrology Dialysis Transplantation.
Hemodialysis Treatments Tied to Increase in Endocarditis Infections
An international study in JAMA reveals that infective endocarditis, infection and inflammation involving the heart valves is commonly associated with being hemodialysis-dependent and is increasingly due to staphylococcal infection.
The Other Stem Cells
Article from Boston Globe. Although embryonic stem cells dominate public discussion, a number of companies are building treatments, and businesses, around adult stem cells.
Doctors Fight over Drug Firm Influence in Hypertension
Article from The Boston Globe. ''The lines separating marketing from education have been fractured," said the editor of the prestigious American Journal of Hypertension. Disagreements have flared over industry money used to support the hypertension society's educational programs, as well as the propriety of direct industry payments to physicians who serve as lecturers and consultants.
Two Cardiologists Alert Medical Community to Kidney Damage Caused by Heart-Failure Drug
Article from Forbes.com. After taking heat for sticking their necks out concerning data on Johnson & Johnson's Natrecor, the two researchers are being backed up by some of the biggest names in cardiology.
Epoetin Label Change Coming in Europe for Maximum Hemoglobin Level Due to Increased Mortality in Cancer Patient Studies
News article from CancerPage.com. The label on epoetin medications is being updated with a new maximum haemoglobin level following studies showing increased mortality at high haemoglobin levels, a senior Amgen official said on Thursday.

Mark Sampson, UK medical director, told Agence de Presse Medicale that the label would set a therapeutic haemoglobin objective of 12g/dL, coupled with a recommendation not to exceed 13g/dL.

What Is a Kidney Worth?
The Christian Science Monitor is currently running a number of articles on organ trafficking. These include:

Cloning Pioneer Envisions Stem Cell Bank
(AP via Yahoo) South Korean cloning pioneer Hwang Woo-suk said he plans to open a stem cell bank to help speed up the quest  to grow replacement tissue to treat diseases. To treat a patient, researchers would look for a cell line that provides a close match to a patient's immune system, resembling the process now used in finding donors for organ transplants.

"Our ultimate goal is for those with incurable disease to lead social lives, and to recover their humane right to happiness."

 
New England Lawmakers Give Stem Cell Research a Push
China To Ban Trade in Human Organs
Article from AFP via Yahoo. The country has long been accused by human rights groups of taking executed prisoners' organs without their consent -- sometimes while they are still alive -- to use for transplants.
Biotech Drugs: Where Are The Generics?
Article from BusinessWeek.com. "Without concerted action in Washington, patients in the U.S. won't get their hands on such products for years." 
Vermont's Disclosure Law Shows Drug Company Payments to Physicians
Article from TimesArgus.com. Dr. Paul Unger received nearly $75,000 from Amgen over a six-month period.
Switching from Subcutaneous to Intravenous Erythropoietin in Haemodialysis Patients Requires a Major Dose Increase
Advance Access abstract from Nephrology Dialysis Transplantation. 
Pharmaceutical Companies Submit Ghostwritten Articles, Medical Journal Editors Say
Catherine DeAngelis, editor of The Journal of the American Medical Association, says, "This has been going on forever." Before she became an editor, DeAngelis says, she got a call a month asking her to put her name on a paper she didn't write, a practice she describes as "manipulation by for-profits to alter what's in the (medical) literature so they could sell their products." (USA Today)

  May 2005
Pig Organ Transplants to Apes Likely This Year
Article from The Korea Times. Additional article from AFP.
Introduction to Xenotransplantation
Article from Science &Theology News. Xenotransplantation involves transplanting living cells, tissues or organs between species, and in particular, from animals to humans
Can ACE Inhibitor Therapy Reverse Kidney Failure?
David W. Moskowitz, MD, is interviewed by Gordon Lore in Nephrology Incite. Moskowitz treated around 1,000 of his own patients based on his research that many diseases are caused in part by ACE. His early efforts reportedly reduced kidney disease caused by hypertension by an average of 300% in both Caucasian and African American male patients! This new treatment indicated that patients who would normally require dialysis in four years were not predicted to reach End-Stage Renal Disease (ESRD) for 16 years!
Bush Would Veto House Bill on Stem Cells
New EPO Formulation from Cuba Compared to Eprex® in Hemodialysis Patients with Anemia: A Parallel, Randomized, Double Blind Study
Abstract from BMC Nephrology. A new EPO preparation from Cuba was compared with Eprex and was found comparable. This is a Free Access article with a provisional PDF file available for download. 
Pig Organ Transplants to Apes Likely This Year
Article from The Korea Times. Addtional article from AFP.
Introduction to Xenotransplantation
Article from Science &Theology News. Xenotransplantation involves transplanting living cells, tissues or organs between species, and in particular, from animals to humans.
Bush Would Veto House Bill on Stem Cells
Reuters article via Yahoo.
The Human Nephron Filter: Toward a Continuously Functioning, Implantable Artificial Nephron System
Abstract from Blood Purification. Read about the company Biophiltre on this page from Red Herring about nanotechnology startups. Also, see Biophiltre founder Gayle Pergamit give a short presentation on her company's prospective product.
Scientists Create Stem Cells That Are Genetic Match to Donors
Article from Reuters via Yahoo. South Korean scientists who cloned the first human embryo to use for research said on Thursday they have used the same technology to create batches of embryonic stem cells from nine patients.
Cloned Human Embryos Deliver Tailored Stem Cells
Article from NewScientist.com.
Stem-Cell Board Too Close to Industry, Critics Worry
Story from Mercury News via SiliconValley.com. California's new stem-cell institute is poised to begin spending $3 billion in public money for research, but watchdogs are worried about whether the board can distribute the money free of industry influence. 
Med Journals 'Too Close to (Drug) Firms'
Medical journals are an extension of the marketing arms of drug firms, says an ex-British Medical Journal editor. (BBC
States Face "Meltdown" over Medicaid
States are already struggling with budget shortfalls and proposed program reductions that could hit both physicians and patients. (American Medical News) 
Drug Industry Admits It Has Been Its Own Worst Enemy
Article from the Boston Globe. 
2nd World Congress on Regenerative Medicine
April issue of the International Journal of Artificial Organs.
Amgen Seen Benefiting From Growing Anemia Market
Article from Forbes.com. 
VC Firms Ready for Stem-Cell Research Efforts
San Jose Mercury News via TimesLeader.com. There's nothing like new money -- $3 billion of it -- to launch a new era in the venture capital community.
Erythropoietin Current Market Dynamics & Future Outlook
Research and Markets press release via PRNewswire. The market has been growing at an average annual growth rate of 18% over the previous 5 years. Since the market is a virtual oligopoly barriers to entry are high thus insuring high profitability.
Drug Innovation Beats Marketing, Patents and Mergers
Wisconsin Technology Network. "The message here is that focused and productive R&D churning out innovative new drugs is currently winning the day over M&A, marketing and even savvy intellectual property strategies to manage product life cycle management. "
Fresenius Medical Care To Buy Renal Care Group Inc.
Story from Bloomberg News. Fresenius Medical Care AG, the world's largest provider of kidney dialysis, agreed to buy Renal Care Group Inc. for $3.5 billion to add patients and treatment centers in the U.S. and fend off mounting competition from DaVita Inc.

 


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