Peritoneal function in clinical practice: the importance of follow-up and its measurement in patients. Recommendations for patient information and measurement of peritoneal function - Annemieke M. Coester, Watske Smit, Dirk G. Struijk, and Raymond T. Krediet

Link to full text article.  NDT Plus - 2:2:104-110 - April 2009  
A review is given on peritoneal function, especially ultrafiltration and ultrafiltration failure followed by recommendations on how to translate pathophysiology into clinical practice. The subsequent consequences for management of peritoneal membrane function and for patient information are also included.

Higher daily peritoneal protein clearance when initiating peritoneal dialysis is independently associated with peripheral arterial disease (PAD): A possible new marker of systemic endothelial dysfunct - Rafael Sánchez-Villanueva, Auxiliadora Bajo, Gloria del Peso, M-Jose Fernandez-Reyes, Elena González, Sara Romero, Patricia Estrada, and Rafael Selgas

Link to abstract.  Nephrology Dialysis Transplantation - 24:3:1009-1014 - March 2009  
Our study shows that daily peritoneal PrC on initiating PD is significantly and independently related to the presence of PAD. Peritoneal PrC appears to be a possible new marker of systemic endothelial dysfunction.

Why do patients on peritoneal dialysis have low blood levels of protein-bound solutes? - Raymond Vanholder, Natalie Meert, Wim Van Biesen, Timothy Meyer, Thomas Hostetter, Annemieke Dhondt and Sunny Eloot

Link to full text article.  Nature Clinical Practice Nephrology - 5:3:130-131 - March 2009  
In conclusion, the discrepancy between the lower blood concentration and lower clearance of pathologically relevant protein-bound solutes in patients on peritoneal dialysis compared with patients on hemodialysis is currently unexplained, but differences in intestinal generation or metabolism of these solutes are likely to be responsible. This hypothesis should be tested in future investigations.

Improvement in Sleep Apnea during Nocturnal Peritoneal Dialysis Is Associated with Reduced Airway Congestion and Better Uremic Clearance - Sydney C. W. Tang, Bing Lam, Andrew S. H. Lai, Clara B. Y. Pang, Wai Kuen Tso, Pek Lan Khong, Mary S. M. Ip, and Kar Neng Lai

Link to abstract.  Clinical Journal of the American Society of Nephrology - 4:2:410-418 - February 2009  
Improvement in sleep apnea during NPD versus CAPD is associated with better fluid and uremic clearance and reduced upper airway congestion during sleep.

POLYNEUROPATHY IN DIABETIC AND NONDIABETIC PATIENTS ON CAPD: IS THERE AN ASSOCIATION WITH HRQOL? - Dijana B. Jovanovic, Dragana D. Matanovic, Sanja P. Simic–Ogrizovic, Milan D. Stosovic, Ana C. Bontic, Vidosava D. Nesic

Link to abstract.  Peritoneal Dialysis International - 29:1:102-107 - January/February 2009  
Polyneuropathy was significantly worse in diabetic than in nondiabetic patients on CAPD. DML on the tibial nerve correlated with glucose concentration, dialysis adequacy, PCS, and MCS in diabetic patients, whereas in nondiabetic patients, dialysis adequacy and azotemia correlated with F-waves on the peroneal nerve and the tibial nerve but MCS only with F-wave on the tibial nerve.

KINETIC ANALYSIS OF PERITONEAL FLUID AND SOLUTE TRANSPORT WITH COMBINATION OF GLUCOSE AND ICODEXTRIN AS OSMOTIC AGENTS - Magda Galach, Andrzej Werynski, Jacek Waniewski, Philippe Freida, Bengt Lindholm

Link to abstract.  Peritoneal Dialysis International - 29:1:72-80 - January/February 2009  
The simulations described well clinical data that showed a dramatic increase in ultrafiltration and sodium removal with the CIG fluid in comparison with the two other dialysis fluids. However, to adapt the three-pore model to the selected group of PD patients (fast transporters with small ultrafiltration capacity on average), the peritoneal pore structure had to be modified. As the mathematical model was capable of reproducing the clinical data, this shows that the enhanced ultrafiltration with the combination fluid is caused by the additive effect of the two different osmotic agents and not by a specific impact of the new dialysis fluid on the transport characteristics of the peritoneum.