The Protein Equivalent of Nitrogen Appearance in Critically Ill Acute Renal Failure Patients Undergoing Continuous Renal Replacement Therapy - Muthusamy V. Ganesan, Rajeev A. Annigeri, Bhuvaneswari Shankar, Budithi Subba Rao, Kowdle C. Prakash, Rajagopalan Seshadri, Muthu Krishna Mani

Link to abstract.  Journal of Renal Nutrition - 19:2:161-166 - March 2009  
Malnutrition was uncommon in patients with acute renal failure at the time of initiation on CRRT, but their total body water was increased. They exhibited hypercatabolism and the mean normalized PNA was 1.57 g/kg/day. A large negative nitrogen balance was observed in them, since their protein intake was suboptimal.

Nursing for Renal Replacement Therapies in the Intensive Care Unit: Historical, Educational, and Protocol Review - Ian Baldwin, Nigel Fealy

Link to full text article. (pdf format requires Adobe Acrobat reader)  Blood Purification - 27:2:174-181 - February 2009  
This review has provided an education focus for the history of dialysis nursing and basic concepts of how CRRT works. This information sets the basis for a policy document necessary in any clinical area where CRRT is applied. All the necessary and sequential steps for a treatment are described. They are patient and machine – circuit preparation, connection of the extracorporeal circuit to the patient vascular access catheter and nursing management of a treatment in progress. This management included fluids preparation, adjustment of fluid settings and electrolyte additives to provide fluid balance, acid base and electrolyte control, and monitoring of patient and machine ‘vital signs’. The final step discussed is the diagnosis of ‘circuit clotting’ and how to perform a disconnection of the circuit and machine from the patient.

The anticoagulant activity of enoxaparin sodium during on-line hemodiafiltration and conventional hemodialysis - Kostas I. SOMBOLOS, Theodora K. FRAGIA, Lazaros C. GIONANLIS, Panagiota E. VENETI, Gerasimos I. BAMICHAS, Stelios K. FRAGIDIS, Ioannis E. GEORGOULIS, Taïsir A. NATSE

Link to full text article.  Hemodialysis International - 13:1:43-47 - January 2009  
The anticoagulant activity of enoxaparin sodium is decreased significantly during a 4-hour OL-HDF session compared with to a similar session of C-HD. The degree of the reduction seems to depend on the dialyzer's membrane.

Intermittent versus continuous renal replacement therapy for acute kidney injury patients admitted to the intensive care unit: results of a randomized clinical trial - Robert L. Lins, Monique M. Elseviers, Patricia Van der Niepen, Eric Hoste, Manu L. Malbrain, Pierre Damas, Jacques Devriendt, and for the SHARF investigators

Link to full text article.  Nephrology Dialysis Transplantation - 24:2:512-518 - February 2009  
Modality of RRT, either CRRT or IRRT, had no impact on the outcome in ICU patients with AKI. Both modalities need to be considered as complementary in the treatment of AKI.

Effective removal of protein-bound uraemic solutes by different convective strategies: a prospective trial - Natalie Meert, Sunny Eloot, Marie-Anne Waterloos, Maria Van Landschoot, Annemieke Dhondt, Griet Glorieux, Ingrid Ledebo, and Raymond Vanholder

Link to full text article.  Nephrology Dialysis Transplantation - 24:2:562-570 - February 2009  
It is concluded that post-dilution is superior to pre-dilution HDF under conditions of similar convective volume, and that HDF is superior to HF in pre-dilution, with the exception of removal of β2M. Overall, post-HDF is the most efficient convective strategy among those tested.

Validity of Internal Filtration-Enhanced Hemodialysis as a New Hemodiafiltration Therapy - Michio Mineshima, Isamu Ishimori, Ryoichi Sakiyama

Link to abstract.  Blood Purification - 27:1:33-37 - January 2009  
The validity of IFEHD was clarified during the experimental studies. Development of a dialyzer with enhanced IF, however, should take account of the patient's safety. Contaminations such as endotoxin invasion from the dialysate to the patient should be avoided.